Tomik J, Składzien J, Modrzejewski M
Otolaryngological Clinic Collegium Medicum, Jagiellonian University, Cracow, Poland.
Auris Nasus Larynx. 2001 Aug;28(3):233-40. doi: 10.1016/s0385-8146(00)00116-4.
The main goal of the paper was to evaluate the results of surgical treatment of patients with laryngeal carcinoma, among whom cervical lymph node metastases were observed. The results of treatment were assessed after prior analysis of the following factors localization of laryngeal carcinoma, local and regional advancement, number of lymph nodes affected by metastases, the incidence of 'occult metastases', the presence of metastases in the pre-laryngeal node, the regions of the neck which were most frequently affected by metastases and supplementary irradiation treatment.
An analysis of a group of 1400 patients who underwent surgery for laryngeal carcinoma in the period 1948-1992, was carried out. In all of the cases, a partial or total laryngectomy accompanied by a unilateral or bilateral surgery of the cervical lymph node system was performed. The results of the above treatment were assessed over a 5-year survival period.
In patients among whom metastases to the lymph nodes were observed, it is the following factors that exert an influence on survival chances: supraglottic and glottic localization of the tumor, an increase of regional and organ advancement of the tumor, number of lymph nodes affected by metastases, the presence of metastases in the 'pre-laryngeal' node and the level of the neck affected by metastases.
The incidence of metastases in regional lymph nodes is a prognostic factor in the treatment of patients suffering from laryngeal carcinoma.
本文的主要目的是评估喉癌患者手术治疗的结果，这些患者伴有颈部淋巴结转移。在对以下因素进行预先分析后评估治疗结果：喉癌的定位、局部和区域进展情况、受转移影响的淋巴结数量、“隐匿性转移”的发生率、喉前淋巴结转移的存在情况、颈部最常受转移影响的区域以及辅助放疗。
对1948年至1992年期间接受喉癌手术的1400例患者进行分析。所有病例均进行了部分或全喉切除术，并伴有单侧或双侧颈部淋巴结系统手术。在5年生存期内评估上述治疗的结果。
在观察到有淋巴结转移的患者中，以下因素对生存机会有影响：肿瘤的声门上和声门定位、肿瘤区域和器官进展程度的增加、受转移影响的淋巴结数量、“喉前”淋巴结转移的存在情况以及受转移影响的颈部水平。
区域淋巴结转移的发生率是喉癌患者治疗中的一个预后因素。
