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听觉系统:功能磁共振成像

Auditory system: functional magnetic resonance imaging.

作者信息

Seifritz E, Di Salle F, Bilecen D, Radü E W, Scheffler K

机构信息

Department of Psychiatry, University of Basel, Basel, Switzerland.

出版信息

Neuroimaging Clin N Am. 2001 May;11(2):275-96, ix.

PMID:11489740
Abstract

Functional MR imaging (fMRI) is being used increasingly to explore the human central auditory system. The considerable background noise produced by echo-planar imaging (EPI) and other fMRI sequences, however, interferes in an unpredictable way with the experimental stimuli. Several approaches exist to overcome this problem. Each has its advantages and disadvantages. These different approaches allow researchers to tailor the experimental designs to specific research questions. Recent studies have yielded significant information about human auditory function. Compared with other sensory systems such as the visual system, the auditory database still is relatively small. It is expected that novel methodologic approaches will stimulate scientific exploration of auditory processing and eventually lead to clinically meaningful applications of auditory fMRI.

摘要

功能磁共振成像(fMRI)正越来越多地用于探索人类中枢听觉系统。然而,回波平面成像(EPI)和其他fMRI序列产生的大量背景噪声,以一种不可预测的方式干扰实验刺激。有几种方法可以克服这个问题。每种方法都有其优缺点。这些不同的方法使研究人员能够根据特定的研究问题调整实验设计。最近的研究已经产生了关于人类听觉功能的重要信息。与视觉系统等其他感觉系统相比,听觉数据库仍然相对较小。预计新的方法将刺激对听觉处理的科学探索,并最终导致听觉fMRI在临床上有意义的应用。

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