Meisenzahl E M, Schlösser R
Department of Psychiatry, Ludwig-Maxmilians University of Munich Medical School, Munich, Germany.
Neuroimaging Clin N Am. 2001 May;11(2):365-74, x.
Advanced functional imaging techniques now make it possible to study in vivo the relationship between altered cerebral activation patterns and the psychopathologic and cognitive features of psychiatric disorders. Functional MR imaging (fMRI) offers new approaches to research questions in psychiatry that could not have been addressed earlier by positron emission tomography and single photon emission CT. Basic features of the biology of psychiatric disorders now can be elucidated by means of fMRI. Study designs involving fMRI capitalize on the technique's enhanced spatial and temporal resolution, noninvasive nature, and absence of radiation exposure.
先进的功能成像技术现在使人们能够在活体中研究大脑激活模式改变与精神疾病的精神病理和认知特征之间的关系。功能磁共振成像(fMRI)为精神病学研究问题提供了新方法,而正电子发射断层扫描和单光子发射计算机断层扫描此前无法解决这些问题。现在可以通过fMRI阐明精神疾病生物学的基本特征。涉及fMRI的研究设计利用了该技术增强的空间和时间分辨率、非侵入性以及无辐射暴露的特点。