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用于测量Oddi括约肌运动功能的套管传感器的研发

Development of a sleeve sensor for measurement of sphincter of Oddi motility.

作者信息

Craig A G, Omari T, Lingenfelser T, Schloithe A C, Saccone G T, Dent J, Toouli J

机构信息

Dept. of General and Digestive Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia 5042.

出版信息

Endoscopy. 2001 Aug;33(8):651-7. doi: 10.1055/s-2001-16211.

DOI:10.1055/s-2001-16211
PMID:11490379
Abstract

BACKGROUND AND STUDY AIMS

Unavoidable catheter movement during sphincter of Oddi (SO) manometry can produce considerable variations in the basal pressure, due to movement of the recording sidehole. The sleeve sensor is a perfused channel which records the highest pressure point along its length. The aim of the study was to develop and evaluate a prototype sleeve sensor for SO manometry.

MATERIALS AND METHODS

Bench-testing was used to assess the dynamic performance of the sleeve and sidehole assemblies. Recordings were initially made with a standard triple-lumen catheter and then with a purpose-built manometric assembly which had a 15 mm long sleeve sensor.

RESULTS

A perfusion rate of 0.04 ml/min gave the best balance between baseline pressure offset and rise rate. Recordings were attempted in nine patients and successfully achieved in four. The sleeve and sidehole recordings of the maximal basal pressure did not differ significantly (mean +/- SEM, 86.1 +/- 26.5 mmHg vs. 90.1 +/- 21.0 mmHg, P = 0.57, r = 0.998).

CONCLUSIONS

Unnecessarily high perfusion rates are being used for SO manometry. The sleeve sensor has the potential to monitor SO pressure more reliably than the currently used perfused sidehole method and should enhance the safety of prolonged SO manometry.

摘要

背景与研究目的

在Oddi括约肌(SO)测压过程中,由于记录侧孔的移动,导管不可避免地会发生移动,这会导致基础压力产生相当大的变化。套管传感器是一个灌注通道,可沿其长度记录最高压力点。本研究的目的是开发并评估一种用于SO测压的原型套管传感器。

材料与方法

采用台架试验评估套管和侧孔组件的动态性能。最初使用标准三腔导管进行记录,然后使用带有15毫米长套管传感器的特制测压组件进行记录。

结果

0.04毫升/分钟的灌注速率在基线压力偏移和上升速率之间达到了最佳平衡。对9名患者进行了记录尝试,4名患者成功完成记录。套管和侧孔记录的最大基础压力无显著差异(平均值±标准误,86.1±26.5毫米汞柱对90.1±21.0毫米汞柱,P = 0.57,r = 0.998)。

结论

目前SO测压使用的灌注速率过高。套管传感器有可能比目前使用的灌注侧孔法更可靠地监测SO压力,并应提高长时间SO测压的安全性。

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Curr Gastroenterol Rep. 2005 May;7(2):154-9. doi: 10.1007/s11894-005-0054-5.
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Normal sphincter of oddi motor function.正常的Oddi括约肌运动功能。
Curr Gastroenterol Rep. 2004 Apr;6(2):163-8. doi: 10.1007/s11894-004-0044-z.