Fedoseev A V, Tarasenko S V, Zaĭtsev O V
Anesteziol Reanimatol. 2001 Mar-Apr(2):48-51.
A new method for lymph detoxication in patients with pyoresorptive endotoxicosis is proposed. The method is based on electrochemical oxidation of the lymph, is simple and cheap. After 4-h exposure of the lymph with 0.04% sodium hypochlorite the concentration of the main toxic metabolites appreciably decreased, while the levels of total protein and leukocytes changed negligibly. Electrochemical detoxication of the lymph was used in the treatment of 13 patients with pyoresorptive endotoxicosis and led to improvement of the clinical status and rapid decrease in the levels of the major toxic metabolites, which was particularly expressed 3 days after the treatment. No negative effects were observed. Hence, electrochemical detoxication of the lymph appreciably improved the results of treatment of patients with cholestatic endotoxicosis.
提出了一种用于治疗化脓性吸收性内毒素血症患者淋巴解毒的新方法。该方法基于淋巴的电化学氧化,简单且成本低廉。用0.04%的次氯酸钠对淋巴进行4小时处理后,主要有毒代谢产物的浓度显著降低,而总蛋白和白细胞水平的变化可忽略不计。对13例化脓性吸收性内毒素血症患者采用淋巴电化学解毒治疗,改善了临床状况,主要有毒代谢产物水平迅速下降,治疗后3天表现尤为明显。未观察到不良反应。因此,淋巴电化学解毒显著改善了胆汁淤积性内毒素血症患者的治疗效果。