Glauser F L, Otis P T, Levine R I, Smith W R
Chest. 1975 Aug;68(2):205-8. doi: 10.1378/chest.68.2.205.
Twenty-three specimens of pleural fluid from 23 patients were examined for quantitative fibrinogen, total protein levels, and for clottability in vitro using the recalcification time. Of the 19 specimens of pleural fluid from patients without loculation, 11 (seven exudates) had no detectable fibrinogen; another 8 (six exudates) had a mean fibrinogen level of 55.0 +/- 10.2 mg percent, and a mean recalcification time of 19.4 +/- 2.6 minutes. The pleural fluids from the four patients with loculation had no detectable fibrinogen. The only fluids containing fibrinolytic activity were from the nonloculated non-fibrinogen-containing group. No correlation existed between pleural fluid/plasma total protein ratios and pleural fluid/plasma fibrinogen ratios. In vitro clottability in this study did not reflect the in vivo tendency for coagulation and loculation.
对23例患者的23份胸水样本进行了检测，以测定其纤维蛋白原定量、总蛋白水平，并通过复钙时间检测体外凝块形成能力。在19例无包裹性积液患者的胸水样本中，11份（7份渗出液）未检测到纤维蛋白原；另外8份（6份渗出液）的纤维蛋白原平均水平为55.0±10.2mg%，平均复钙时间为19.4±2.6分钟。4例有包裹性积液患者的胸水样本未检测到纤维蛋白原。唯一含有纤溶活性的样本来自无包裹性积液且不含纤维蛋白原的组。胸水/血浆总蛋白比值与胸水/血浆纤维蛋白原比值之间无相关性。本研究中的体外凝块形成能力并未反映体内的凝血和包裹性积液倾向。
