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胸腔积液中的凝血因子和纤维蛋白原。

Coagulation factors and fibrinogen in pleural effusions.

作者信息

Glauser F L, Otis P T, Levine R I, Smith W R

出版信息

Respiration. 1976;33(5):396-402. doi: 10.1159/000193755.

DOI:10.1159/000193755
PMID:935693
Abstract

31 pleural effusions from 27 patients with varied diseases were studied for specific coagulation factors and fibrinogen. In all fluids, exudates had a higher content of factors and fibrinogen than transudates. When pleural fluid to plasma total protein ratios were compared to specific coagulation factors a positive correlation existed for all. This was not true for fibrinogen. There was a poor correlation between the molecular weights of the specific factors and fibrinogen and their appearance in the pleural fluid. The concentration of factor XII in 35% and factor XI in 11% of pleural fluid exceeded their respective plasma concentration.

摘要

对27例患有各种疾病的患者的31份胸腔积液进行了特定凝血因子和纤维蛋白原的研究。在所有积液中,渗出液中因子和纤维蛋白原的含量高于漏出液。当将胸腔积液与血浆总蛋白比值与特定凝血因子进行比较时,所有指标均呈正相关。纤维蛋白原情况并非如此。特定因子和纤维蛋白原的分子量与其在胸腔积液中的出现之间相关性较差。35%的胸腔积液中因子XII浓度和11%的胸腔积液中因子XI浓度超过了各自的血浆浓度。

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