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早期精神分裂症失代偿的临床识别

Clinical recognition of early schizophrenic decompensation.

作者信息

Donlon P T, Blacker K H

出版信息

Dis Nerv Syst. 1975 Jun;36(6):323-7.

PMID:1149591
Abstract

The early signs and symptoms of schizophrenic decompensation are subtle and variegated. Today's community patient often presents with vague complaints of brief duration making it imperative that today's diagnostician be able to recognize and appropriately treat early psychopathology. This paper collates a number of observations of developing psychotic phenomena -- self reports, clinical studies and controlled experiments -- and provides a useful format for organizing these complex and changing behaviors. Data are presented and discussed using our clinical schema for detailing the natural progression of developing psychotic phenomena into four distinct stages. Efficacy of early recognition and treatment in aborting or diminishing a major psychotic episode is discussed. The advantages of recognizing the early signs of psychotic decompensation are apparent. First, with adequate intervention and treatment, the overt psychotic state may be attenuated. Although the feasibility of reducing the incidence of schizophrenia through intervention in "high risk" groups, or those experiencing insidious symptoms remain speculative (further investigation in this area is urgently needed), nonetheless, early diagnosis and comprehensive rehabilitative care significantly improves social and occupational adjustment. A second advantage accrues from early diagnosis. It enables patient and family to better cope with the illness. We have previously outlined a schema detailing the natural progression of developing psychotic phenomena into four distinct stages. The phenomena, when identified, can be seen as a continuum. However, many clinicians fail to recognize the earlier phases and typically the diagnosis of psychosis is made relatively late at what we call stage three of the four stages we described.

摘要

精神分裂症失代偿的早期症状微妙且多样。如今的社区患者常常表现出持续时间短暂的模糊主诉,这使得当今的诊断医生必须能够识别并妥善治疗早期精神病理学症状。本文整理了一些关于精神病性现象发展的观察结果——自我报告、临床研究和对照实验——并提供了一种有用的形式来组织这些复杂且不断变化的行为。我们使用临床模式来呈现和讨论数据,该模式将精神病性现象发展的自然进程详细划分为四个不同阶段。文中还讨论了早期识别和治疗在中止或减轻重大精神病发作方面的效果。识别精神分裂症失代偿早期迹象的益处显而易见。首先,通过充分的干预和治疗,明显的精神病状态可能会得到缓解。尽管通过干预“高危”群体或那些出现隐匿症状的人群来降低精神分裂症发病率的可行性仍有待推测(这一领域迫切需要进一步研究),但早期诊断和全面的康复护理能显著改善社会和职业适应能力。早期诊断的第二个益处在于,它能使患者及其家属更好地应对疾病。我们之前已经概述了一个模式,将精神病性现象发展的自然进程详细划分为四个不同阶段。这些现象一旦被识别,可视为一个连续体。然而,许多临床医生未能识别早期阶段,通常在我们所描述的四个阶段中的第三阶段才做出精神病的诊断,且诊断相对较晚。

相似文献

1
Clinical recognition of early schizophrenic decompensation.早期精神分裂症失代偿的临床识别
Dis Nerv Syst. 1975 Jun;36(6):323-7.
2
[Frontal dementia or dementia praecox? A case report of a psychotic disorder with a severe decline].[额颞叶痴呆还是早发性痴呆?一例伴有严重衰退的精神障碍病例报告]
Encephale. 2003 Mar-Apr;29(2):172-80.
3
Early detection and intervention of psychosis. A review.精神病的早期检测与干预。综述。
Nord J Psychiatry. 2008;62(2):92-105. doi: 10.1080/08039480801984008.
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[Pre-psychotic states--contemporary diagnostic and therapeutic issues. Part I. Clinical identification of pre-psychotic states].[精神病前期状态——当代诊断与治疗问题。第一部分。精神病前期状态的临床识别]
Psychiatr Pol. 2007 Jan-Feb;41(1):5-15.
5
[Psychopathology of schizophrenia and brain imaging].[精神分裂症的精神病理学与脑成像]
Fortschr Neurol Psychiatr. 2008 May;76 Suppl 1:S49-56. doi: 10.1055/s-2008-1038152.
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[Interest of a new instrument to assess cognition in schizophrenia: The Brief Assessment of Cognition in Schizophrenia (BACS)].[一种用于评估精神分裂症认知功能的新工具的价值:精神分裂症认知功能简短评估量表(BACS)]
Encephale. 2008 Dec;34(6):557-62. doi: 10.1016/j.encep.2007.12.005. Epub 2008 Jul 9.
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[Prodromal symptoms of schizophrenia].[精神分裂症的前驱症状]
Encephale. 2003 Nov-Dec;29(6):469-77.
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Exploring the borders of the schizoaffective spectrum: a categorical and dimensional approach.探索分裂情感性谱系的边界:一种分类与维度方法。
J Affect Disord. 2008 May;108(1-2):71-86. doi: 10.1016/j.jad.2007.09.009. Epub 2007 Oct 29.
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[Is there any point in detecting high risk factors prior to a first psychosis?].[在首次精神病发作之前检测高危因素有意义吗?]
Tijdschr Psychiatr. 2006;48(6):467-76.
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[Duration of untreated psychosis in first-episode schizophrenia: clinical and cognitive correlates].[首发精神分裂症未治疗精神病期:临床及认知相关性]
Psychiatr Pol. 2005 Sep-Oct;39(5):859-68.

引用本文的文献

1
Preferences for different insomnia treatment options in people with schizophrenia and related psychoses: a qualitative study.精神分裂症及相关精神病患者对不同失眠治疗方案的偏好:一项定性研究
Front Psychol. 2015 Jul 14;6:990. doi: 10.3389/fpsyg.2015.00990. eCollection 2015.
2
Sleep disturbances in patients with schizophrenia : impact and effect of antipsychotics.精神分裂症患者的睡眠障碍:抗精神病药物的影响及作用
CNS Drugs. 2008;22(11):939-62. doi: 10.2165/00023210-200822110-00004.