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Is phlorizin or its aglycon the inhibitor of intestinal glucose transport? A study in normal and lactase deficient man.

作者信息

Blum A L, Haemmerli U P, Lorenz-Meyer H

出版信息

Eur J Clin Invest. 1975 Jun 12;5(3):285-8. doi: 10.1111/j.1365-2362.1975.tb00456.x.

DOI:10.1111/j.1365-2362.1975.tb00456.x
PMID:1149786
Abstract

Inhibition of glucose transport by phlorizin was examined in man by perfusion of an isolated small bowel segment. Inhibition was similar in normal and lactase deficient subjects. Since the small bowel of lactase deficient subjects contains only very small amounts of phlorizin hydrolase, phlorizin and not a product of enzymatic cleavage is the inhibitor of the small intestinal glucose carrier.

摘要

相似文献

1
Is phlorizin or its aglycon the inhibitor of intestinal glucose transport? A study in normal and lactase deficient man.
Eur J Clin Invest. 1975 Jun 12;5(3):285-8. doi: 10.1111/j.1365-2362.1975.tb00456.x.
2
Interaction of phlorizin and phloretin with glucose transport system of the pigeon intestine.根皮苷和根皮素与鸽肠道葡萄糖转运系统的相互作用。
Indian J Biochem Biophys. 1986 Aug;23(4):208-11.
3
An example of mutual competition between transport inhibitors of different kinetic type: the inhibition of intestinal transport of glucalogues by phloretin and phlorizin.不同动力学类型的转运抑制剂之间相互竞争的一个例子：根皮素和根皮苷对肠道中糖类似物转运的抑制作用。
Biochim Biophys Acta. 1972 Oct 23;288(1):145-52. doi: 10.1016/0005-2736(72)90232-5.
4
Inhibition of glucose absorption by phlorizin affects intestinal functions in rats.根皮苷对葡萄糖吸收的抑制作用影响大鼠的肠道功能。
Gastroenterology. 1993 Sep;105(3):692-7. doi: 10.1016/0016-5085(93)90884-f.
5
Effects of lactose on intestinal calcium absorption in normal and lactase-deficient subjects.乳糖对正常受试者和乳糖酶缺乏受试者肠道钙吸收的影响。
Gastroenterology. 1983 May;84(5 Pt 1):935-40.
6
Effects of ketohexosemia on the ketohexose transport in the small intestine of rats.己酮糖血症对大鼠小肠中己酮糖转运的影响。
Biochim Biophys Acta. 1984 May 30;772(3):259-63. doi: 10.1016/0005-2736(84)90142-1.
7
Competitive inhibition of intestinal glucose transport by phlorizin analogs.根皮苷类似物对肠道葡萄糖转运的竞争性抑制作用。
Arch Biochem Biophys. 1966 Nov;117(2):248-56. doi: 10.1016/0003-9861(66)90409-7.
8
Intestinal Na+/glucose cotransporter-mediated transport of glucose conjugate formed from disaccharide conjugate.肠道钠/葡萄糖协同转运蛋白介导由二糖缀合物形成的葡萄糖缀合物的转运。
Biochim Biophys Acta. 1998 Jan 8;1379(1):1-6. doi: 10.1016/s0304-4165(97)00074-3.
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Isoosmotic transport of fluid across the hamster small intestine in the presence of phlorizin-induced inhibition of sugar transport.在根皮苷诱导的糖转运抑制存在的情况下，液体跨仓鼠小肠的等渗转运。
Can J Physiol Pharmacol. 1975 Jun;53(3):375-82. doi: 10.1139/y75-054.
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Effect of phloretin on Na+-dependent D-glucose uptake by intestinal brush border membrane vesicles.根皮素对肠刷状缘膜囊泡钠依赖性葡萄糖摄取的影响。
Biochem Pharmacol. 1983 Nov 15;32(22):3453-7. doi: 10.1016/0006-2952(83)90376-3.

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