Caplan Y H, Goldberger B A
National Scientific Services, Baltimore, Maryland 21208, USA.
J Anal Toxicol. 2001 Jul-Aug;25(5):396-9. doi: 10.1093/jat/25.5.396.
Recent advances in analytical techniques have enabled the detection of drugs and drug metabolites in alternative biological specimens for the purposes of workplace testing. A wide variety of specimens are available, each providing valuable information concerning prior or current drug use. The present focus is on oral fluid (saliva), hair, and sweat. An extensive evaluation by the Division of Workplace Programs of the Department of Health and Human Services is underway to determine the utility of these specimens in federally regulated programs. In future years, the testing of alternative specimens will expand our ability to understand the patterns of drug use and will become routine in all areas of forensic toxicology.
分析技术的最新进展使得在工作场所检测中能够在替代生物样本中检测药物和药物代谢物。有各种各样的样本可供使用,每种样本都能提供有关既往或当前药物使用的有价值信息。目前的重点是口腔液(唾液)、毛发和汗液。美国卫生与公众服务部工作场所项目司正在进行广泛评估,以确定这些样本在联邦监管项目中的效用。在未来几年,替代样本检测将扩大我们了解药物使用模式的能力,并将在法医毒理学的所有领域成为常规检测。