Fung T D, Chertkow H, Murtha S, Whatmough C, Péloquin L, Whitehead V, Templeman F D
Bloomfield Center for Research in Aging, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Neuropsychology. 2001 Jul;15(3):371-9.
The validity and origin of category effects in the anomia demonstrated by individuals with dementia of the Alzheimer's type (DAT) remains controversial. Twenty DAT subjects were tested with picture naming and semantic association judgment tests. Picture and word stimuli were drawn from biological, nonbiological, and actions-verbs categories, all of equal difficulty and previously normed on elderly controls. DAT subjects made significantly more naming and semantic judgment errors in the biological category than in the nonbiological category. They were relatively more accurate in naming and making judgments for actions-verbs when presented as words or as 5-s animations. When line drawings of actions were shown for naming, performance deteriorated significantly. Converging results from these 2 tasks provide strong evidence for a semantic memory impairment preferentially affecting biological items to a greater extent than nonbiological items or action verbs in DAT.
阿尔茨海默病型痴呆（DAT）患者所表现出的失命名症中类别效应的有效性和起源仍存在争议。对20名DAT患者进行了图片命名和语义联想判断测试。图片和单词刺激来自生物、非生物和动作动词类别，所有这些类别难度相同，并且之前已在老年对照组中进行过标准化。DAT患者在生物类别中出现的命名和语义判断错误明显多于非生物类别。当以单词或5秒动画形式呈现时，他们在命名和对动作动词进行判断方面相对更准确。当展示动作的线条图进行命名时，表现显著下降。这两项任务的趋同结果提供了有力证据，表明在DAT中，语义记忆障碍对生物项目的影响比对非生物项目或动作动词的影响更大。
