Liu C, Song R, Song Y
General Military Hospital, Beijing, 100853.
Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1999 Sep;15(5):329-31.
This study was carried out to investigate the histological reactions of midfacial sutures induced by transverse palatal suture expansion.
Nine mongrel dogs of 8-week old were used in the study. Six of them were used as experimental group as described in a previous paper. The additional three served as controls. In the experimental dogs, a NiTi-shape memory alloy (NiTi-SMA) arch wire was used to expand the transverse palatal suture. Tetracycline was injected intramuscularly (50 mg/kg) three days before operation and at the time of sacrifice. Tissue reactions of premaxillo-maxillary suture, transverse palatal suture, zygomatico-maxillary suture, zygomatico-temporal suture and fronto-maxillary suture were observed in undecalcified tetracycline labeled sections and decalcified histological sections.
The sutures in normal young dogs showed active bone formation. With the increase of age, the cellular components of the suture decreased. A great amount of new bone apposition was found in the bony front of expanded transverse palatal suture of the experimental dogs. Degenerative changes were found in premaxillo-maxillary suture at the expanded side while the contralateral showed active osteogenesis. Other sutures manifested both bone apposition and deposition due to the irregular interdigitations.
After expansion, a great amount of new bone formed in the transverse palatal suture and thus the hard palate was lengthened. All the circum-maxillary sutures reacted in different patterns.
本研究旨在探讨横向腭中缝扩展诱导的面中部缝线的组织学反应。
本研究使用了9只8周龄的杂种犬。其中6只作为实验组，如前文所述。另外3只作为对照组。在实验组犬中，使用镍钛形状记忆合金（NiTi-SMA）弓丝扩展横向腭中缝。在手术前3天和处死时肌肉注射四环素（50mg/kg）。在未脱钙的四环素标记切片和脱钙组织学切片中观察前上颌-上颌缝、横向腭缝、颧上颌缝、颧颞缝和额上颌缝的组织反应。
正常幼犬的缝线显示出活跃的骨形成。随着年龄的增加，缝线的细胞成分减少。在实验组犬扩展的横向腭缝的骨前沿发现大量新骨附着。在扩展侧的前上颌-上颌缝发现退行性改变，而对侧显示活跃的成骨作用。由于不规则的交错，其他缝线表现出骨附着和沉积。
扩展后，横向腭缝中形成大量新骨，从而使硬腭延长。所有上颌周围缝线均呈现不同的反应模式。
