Higgs R H, Ellis-Pegler R B, Lambert H P
Gut. 1975 Jun;16(6):458-61. doi: 10.1136/gut.16.6.458.
Intestinal transit times in children less than 3 years old with gastroenteritis were measured using carmine suspension and radioopaque pellets. Carmine transit times were short as expected in the acute illness, and lengthened on recovery to the values found in children without diarrhoea. Pellet transit times of the sick children were the same as those of controls without bowel disease. Solid markers may thus be misleading in acute diarrhoeal illness of childhood. Possible mechanisms are discussed.
采用胭脂红悬液和不透X线小丸对3岁以下患肠胃炎儿童的肠道转运时间进行了测量。正如预期的那样,在急性疾病期间胭脂红的转运时间较短,而在恢复时延长至无腹泻儿童的水平。患病儿童的小丸转运时间与无肠道疾病的对照组相同。因此,在儿童急性腹泻病中,固体标志物可能会产生误导作用。文中讨论了可能的机制。