Nakagomi T, Correia J B, Nakagomi O, Montenegro F M U, Cuevas L E, Cunliffe N A, Hart C A
Department of Medical Microbiology and Genitourinary Medicine, University of Liverpool, Liverpool, UK.
Arch Virol. 2008;153(5):957-60. doi: 10.1007/s00705-008-0060-7. Epub 2008 Mar 4.
Norovirus has captured increasing attention as an agent of childhood diarrhoea. However, it is not known whether norovirus causes as severe diarrhoea as rotavirus, particularly among children in developing countries. In a 1-year study conducted between May 2004 and April 2005 in Recife, Brazil, norovirus was detected by ELISA in 34/233 (15%) diarrhoeal children less than 5 years of age. The severity of clinical illness, as indicated by the presence of dehydration, the requirement for hospitalization, and the duration of hospital stay, was similar between children with norovirus and rotavirus infection. These data underscore the importance of norovirus as a cause of severe diarrhoea in children.
作为导致儿童腹泻的病原体，诺如病毒已受到越来越多的关注。然而，尚不清楚诺如病毒是否会像轮状病毒那样引发严重腹泻，尤其是在发展中国家的儿童中。在2004年5月至2005年4月于巴西累西腓进行的一项为期1年的研究中，通过酶联免疫吸附测定法（ELISA）在233名5岁以下腹泻儿童中的34名（15%）检测到了诺如病毒。诺如病毒感染儿童和轮状病毒感染儿童在脱水情况、住院需求以及住院时间等方面所表明的临床疾病严重程度相似。这些数据强调了诺如病毒作为儿童严重腹泻病因的重要性。
