Obstet Gynecol. 2001 Apr;97(4):suppl 1-13.
According to the U.S. Centers for Disease Control and Prevention, 1.18 million legal abortions were performed in the United States in 1997. Of these, 55.5% were performed at or before 56 days of gestation (calculated from the first day of the last menstrual period [LMP]) (I). Almost 98% of abortion procedures were performed by uterine curettage; all but 1% of these used suction curettage. There were 305 legal induced abortions per 1,000 live births, and the abortion rate was 20 per 1,000 women aged 15-44 years. For the first time in 1997, medical abortions were counted and comprised 0.25% of all abortions; 0.45% of those procedures were performed up to 56 days of gestation. Because of the lack of availability of mifepristone, these procedures mostly represent the use of a combination of methotrexate and misoprostol. Over the past two decades, medical methods of abortion have developed throughout the world and are now used clinically in the United States. This document will present evidence of effectiveness, benefits, and risks of medical methods of abortion and provide a framework for the evaluation and counseling of women who are considering such medical methods.
根据美国疾病控制与预防中心的数据，1997年美国进行了118万例合法堕胎手术。其中，55.5%的手术是在妊娠56天及以内进行的（从末次月经首日[LMP]算起）（I）。几乎98%的堕胎手术采用刮宫术；其中除1%外均采用吸刮术。每1000例活产中有305例合法人工流产，堕胎率为每1000名15至44岁女性中有20例。1997年，药物流产首次被纳入统计，占所有堕胎手术的0.25%；其中0.45%的手术是在妊娠56天及以内进行的。由于米非司酮供应不足，这些手术大多采用甲氨蝶呤和米索前列醇联合使用的方式。在过去二十年中，药物流产方法在全球范围内得到发展，目前在美国也已应用于临床。本文将提供药物流产方法有效性、益处和风险的证据，并为考虑采用此类药物流产方法的女性提供评估和咨询框架。
