Bartz Deborah, Goldberg Alisa
Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Brigham and Women's Hospital, Planned Parenthood League of Massachusetts, Boston, Massachusetts, USA.
Clin Obstet Gynecol. 2009 Jun;52(2):140-50. doi: 10.1097/GRF.0b013e3181a2b026.
Medical methods for pregnancy termination in early gestation offer women an alternative to surgical evacuation and have the potential to improve access globally to safe abortion. Several drug regimens are used with varying efficacy including mifepristone plus misoprostol, misoprostol alone, and methotrexate plus misoprostol. Where available, a mifepristone plus misoprostol regimen is most frequently used and is highly effective for early abortion. We review these drug regimens along with clinical practice recommendations including patient counseling and selection, regimen administration location, expected side effects, and follow-up procedures. Overall, women who choose medical abortion report high levels of satisfaction.
妊娠早期终止妊娠的医学方法为女性提供了手术清宫之外的另一种选择，并且有可能改善全球安全堕胎服务的可及性。几种药物方案的疗效各不相同，包括米非司酮加米索前列醇、单独使用米索前列醇以及甲氨蝶呤加米索前列醇。在有条件的地方，米非司酮加米索前列醇方案使用最为频繁，对早期堕胎非常有效。我们回顾了这些药物方案以及临床实践建议，包括患者咨询与选择、方案给药地点、预期副作用和后续程序。总体而言，选择药物流产的女性报告满意度很高。
