复杂部分性发作儿童及失神性原发性全身性癫痫儿童的精神病理学测量
Measures of psychopathology in children with complex partial seizures and primary generalized epilepsy with absence.
作者信息
Ott D, Caplan R, Guthrie D, Siddarth P, Komo S, Shields W D, Sankar R, Kornblum H, Chayasirisobhon S
机构信息
Neuropsychiatric Institute, Los Angeles, CA, 90024, USA.
出版信息
J Am Acad Child Adolesc Psychiatry. 2001 Aug;40(8):907-14. doi: 10.1097/00004583-200108000-00012.
OBJECTIVE
This investigation examined psychopathology in 48 children with complex partial seizures (CPS), 39 children with primary generalized epilepsy with absence (PGE), and 59 nonepileptic children, aged 5 to 16 years, by comparing the Child Behavior Checklist (CBCL) and the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS).
METHOD
The CBCL was completed by parents and the K-SADS was administered to both parent and child.
RESULTS
The CBCL identified psychopathology in 26% and the K-SADS in 51% of the CPS and PGE patients (kappa = 0.32). The CPS and PGE groups had significantly higher mean CBCL scores, as well as higher rates of psychiatric diagnoses and symptoms of psychopathology, compared with the nonepileptic group. However, the CPS and PGE groups did not differ in these measures. Within each patient group, Full Scale IQ, but not seizure control, was associated with these measures of psychopathology.
CONCLUSION
These findings suggest that the K-SADS identifies more children with psychopathology than the CBCL in children with CPS and PGE.
目的
本研究通过比较儿童行为量表（CBCL）和学龄儿童情感障碍与精神分裂症问卷（K-SADS），对48名患有复杂部分性癫痫（CPS）的儿童、39名患有原发性全面性癫痫伴失神发作（PGE）的儿童以及59名5至16岁的非癫痫儿童的精神病理学进行了检查。
方法
CBCL由家长完成，K-SADS则同时对家长和孩子进行测评。
结果
CBCL在26%的CPS和PGE患者中发现了精神病理学问题，而K-SADS在51%的此类患者中发现了精神病理学问题（kappa值=0.32）。与非癫痫组相比，CPS组和PGE组的CBCL平均得分显著更高，精神疾病诊断率和精神病理学症状发生率也更高。然而，CPS组和PGE组在这些指标上没有差异。在每个患者组中，全量表智商与这些精神病理学指标相关，而癫痫控制情况与之无关。
结论
这些发现表明，在患有CPS和PGE的儿童中，K-SADS比CBCL能识别出更多有精神病理学问题的儿童。
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