Diakomanolis E, Elsheikh A, Voulgaris Z, Rodolakis A, Vlachos G, Michalas S
Department of Obstetrics & Gynecology, University of Athens, Alexandra Hospital, Greece.
Eur J Gynaecol Oncol. 2001;22(3):236-7.
The prevalence of HPV and CIN in young women has increased in recent years. During a 5-year period (1996-2000), 78 sexually active young females, aged 15-20 years, were referred to the Colposcopic Unit of the 1st Department of Obstetrics and Gynecology of the University of Athens in the major University-appointed hospital in Greece, because of an abnormal cytology or a suspicious cervical abnormality in the presence of negative cytology. Colposcopic examinations were found to be within normal limits in 12/78 (15.4%) of cases. Cervical pathology was related in 22 cases (28.2%) to HPV infection, 23 (29.5%) cases to CIN 1, 18 (23.1%) cases to CIN II and 3 (3.8%) to CIN III. No relation between oral contraceptive use and cigarette smoking with HPV infection was found. Our findings strongly confirm the necessity of obtaining cervicovaginal smears on all sexually active gynecologic and obstetric teenage patients.
近年来，年轻女性中人乳头瘤病毒（HPV）和宫颈上皮内瘤变（CIN）的患病率有所上升。在1996年至2000年的5年期间，78名年龄在15至20岁之间、有性活动的年轻女性因细胞学异常或在细胞学检查呈阴性时存在可疑的宫颈异常情况，被转诊至希腊主要大学附属医院雅典大学第一妇产科的阴道镜检查科。经检查发现，78例中有12例（15.4%）阴道镜检查结果正常。22例（28.2%）宫颈病变与HPV感染有关，23例（29.5%）与CIN 1有关，18例（23.1%）与CIN II有关，3例（3.8%）与CIN III有关。未发现口服避孕药的使用及吸烟与HPV感染之间存在关联。我们的研究结果有力地证实了对所有有性活动的妇产科青少年患者进行宫颈阴道涂片检查的必要性。
