氯氮卓增强小鼠抗胆碱能药物诱导的运动兴奋作用。
Enhancement by chlordiazepoxide of the anticholinergic-induced locomotor stimulation in mice.
作者信息
Sansone M, Hano J
出版信息
Psychopharmacology (Berl). 1979 Aug 8;64(2):181-4. doi: 10.1007/BF00496059.
PMID:115038
Abstract
Spontaneous locomotor activity has been studied in mice treated with chlordiazepoxide, atropine, and scopolamine, given alone or in combination. Chlordiazepoxide alone increased activity for a short time, while the two anticholinergic drugs produced longer lasting stimulatory effects. Locomotor stimulation was stronger when chlordiazepoxide and anticholinergics were given in combination.
摘要
已经对单独或联合给予氯氮卓、阿托品和东莨菪碱治疗的小鼠的自发运动活动进行了研究。单独使用氯氮卓会在短时间内增加活动，而两种抗胆碱能药物产生的刺激作用持续时间更长。当联合给予氯氮卓和抗胆碱能药物时，运动刺激更强。
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