氯氮卓 - 吗啡组合对三种近交系小鼠自发运动活性的影响。
Effects of chlordiazepoxide-morphine combinations on spontaneous locomotor activity in three inbred strains of mice.
作者信息
Sansone M, Oliverio A
出版信息
Arch Int Pharmacodyn Ther. 1980 Sep;247(1):71-5.
PMID:7447562
Abstract
Spontaneous locomotor activity has been studied, in three strains of mice, following the administration of morphine and chlordiazepoxide, given alone or in combination. The results demonstrate that chlordiazepoxide enhances the morphine-induced locomotor stimulation in C57/BL/6 and BALB/c mice and counteracts the depressant effect exerted by morphine in DBA/2 mice.
摘要
在单独或联合给予吗啡和氯氮卓后，对三种品系的小鼠的自发运动活性进行了研究。结果表明，氯氮卓增强了吗啡对C57/BL/6和BALB/c小鼠的运动刺激作用，并抵消了吗啡对DBA/2小鼠的抑制作用。
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