在小鼠中亚急性给予氯氮䓬对氯氮䓬 - 苯丙胺组合刺激作用的促进作用。
Facilitation of stimulatory effect of chlordiazepoxide-amphetamine combination by subacute administration of chlordiazepoxide in mice.
作者信息
Sansone M, Renzi P, Vetulani J
出版信息
Psychopharmacology (Berl). 1986;89(1):52-4. doi: 10.1007/BF00175188.
PMID:3090591
Abstract
Spontaneous locomotor activity was tested in CD-1 mice receiving subacutely (for 4 days) chlordiazepoxide (10 mg/kg) and then treated with d-amphetamine (0.5 or 1 mg/kg) and various doses of chlordiazepoxide (2.5, 5 or 10 mg/kg) separately or in combination. Chlordiazepoxide pretreatment enhanced the stimulatory effect of the chlordiazepoxide-amphetamine combination.
摘要
在亚急性（4天）接受氯氮卓（10毫克/千克）的CD-1小鼠中测试自发运动活性，然后分别或联合给予d-苯丙胺（0.5或1毫克/千克）和各种剂量的氯氮卓（2.5、5或10毫克/千克）。氯氮卓预处理增强了氯氮卓-苯丙胺组合的刺激作用。
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