Bradley G A, Orr K, Reggiardo C, Glock R D
Department of Veterinary Science and Microbiology, The University of Arizona, Tucson 85705, USA.
J Wildl Dis. 2001 Jul;37(3):617-20. doi: 10.7589/0090-3558-37.3.617.
Enterotoxigenic Escherichia coli with genes for heat stabile toxins Sta and STb was isolated from the gastrointestinal tract and multiple visceral organs of three adult and three juvenile black-footed ferrets (Mustela nigripes) that died in a captive breeding colony between 24 May 1998 and 2 July 1998. Similar isolates were obtained from rectal swabs of one adult and one juvenile that were clinically ill. All were fed a diet composed of mink chow, raw rabbit meat, beef liver powder, blood meal and lard. Escherichia coli of the same toxin genotype was isolated from the mixed ration. Clinical signs included sudden death, dehydration, anorexia and diarrhea. Necropsy lesions included acute enteritis with large numbers of rod shaped bacteria microscopically visible on intestinal villi.
1998年5月24日至7月2日期间，在一个圈养繁殖群体中死亡的3只成年和3只幼年黑足雪貂（鼬属黑足鼬）的胃肠道和多个内脏器官中，分离出了带有热稳定毒素Sta和STb基因的产肠毒素大肠杆菌。从1只临床患病的成年和1只幼年的直肠拭子中也获得了类似的分离株。所有动物均喂食由貂粮、生兔肉、牛肉肝粉、血粉和猪油组成的日粮。从混合日粮中分离出了相同毒素基因型的大肠杆菌。临床症状包括猝死、脱水、厌食和腹泻。尸检病变包括急性肠炎，在肠道绒毛上显微镜下可见大量杆状细菌。
