Salooja N, Perry D J
Department of Haematology, Charing Cross Hospital, London, UK.
Blood Coagul Fibrinolysis. 2001 Jul;12(5):327-37. doi: 10.1097/00001721-200107000-00001.
Thrombelastography is a 'near patient' test of coagulation. It is easy to perform and can provide information on a patient's coagulation status within 30 min. Despite more than 25 years of clinical experience, however, several basic questions relating thromboelastograph (TEG) parameters to standard coagulation tests remain unanswered, and the value of the TEG is established only in the setting of orthotopic liver transplantation and cardiopulmonary bypass surgery. This review will focus on the principles and practise of the TEG(R), and data supporting the current accepted uses. Potential future uses will also be discussed including evaluation of hypercoagulable states, and investigating the mechanism of coagulopathies due to drugs or disease that standard tests have failed to unravel.
血栓弹力图是一种“床旁”凝血检测方法。它操作简便,能在30分钟内提供患者凝血状态的信息。然而,尽管有超过25年的临床经验,但关于血栓弹力图(TEG)参数与标准凝血检测之间的几个基本问题仍未得到解答,且TEG的价值仅在原位肝移植和体外循环手术中得到确立。本综述将聚焦于TEG(R)的原理与应用,以及支持当前公认用途的数据。还将讨论其潜在的未来用途,包括对高凝状态的评估,以及探究标准检测未能揭示的药物或疾病所致凝血病的机制。