Bailey F, Brittain P N, Williamson B F
J Chromatogr. 1975 Jun 18;109(2):305-12. doi: 10.1016/s0021-9673(01)91803-5.
An automated method for the determination of chlorhexidine (Hibitane) and its salts in formulated pharmaceutical products is described. The equipment consists of a high efficiency liquid chromatograph, a variable wavelength high sensitivity ultraviolet spectrophotometric detector, the output of which is monitored simultaneously by a suitable recorder, and a digital computer. The sample is automatically introduced onto a 10-cm silica gel column by use of a slide valve. Results are calculated and printed out by the computer.
本文描述了一种测定制剂药品中洗必泰（双氯苯双胍己烷）及其盐类的自动化方法。该设备由一台高效液相色谱仪、一台可变波长高灵敏度紫外分光光度检测器（其输出由一台合适的记录仪同时监测）以及一台数字计算机组成。通过滑阀将样品自动注入一根10厘米的硅胶柱。结果由计算机计算并打印出来。
