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通过电感耦合等离子体质谱法测定平原毛丝鼠(Lagostomus maximus)血清和全血中17种微量元素的浓度、其参考范围及其与白内障的关系。

Concentration of 17 trace elements in serum and whole blood of plains viscachas (Lagostomus maximus) by ICP-MS, their reference ranges, and their relation to cataract.

作者信息

Forrer R, Wenker C H, Gautschi K, Lutz H

机构信息

Department of Internal Veterinary Medicine, University of Zurich, Switzerland.

出版信息

Biol Trace Elem Res. 2001 Jul;81(1):47-62. doi: 10.1385/bter:81:1:47.

Abstract

The reference ranges of the trace elements Al, As, Be, B, Cd, Co, Cu, Fe, Mn, Mo, Ni, Pb, Li, Rb, Se, Sr, and Zn were determined by inductively coupled plasma-mass spectrometry (ICP-MS) in sera of a group of free-ranging plains viscachas of the pampa grasslands of Argentina. The values were compared with those of a small group of captive plains viscachas of the Zurich Zoo with diabetes and bilateral cataracts. In addition, a method for digestion of whole-blood samples is described for the trace element determination. Significant differences in the concentration of trace elements in the two groups of animals are discussed. No correlation was found between the levels of selenium and of other trace elements compared to the formation of cataracts.

摘要

采用电感耦合等离子体质谱法(ICP-MS)测定了阿根廷潘帕斯草原一群自由放养的平原棉尾兔血清中微量元素铝(Al)、砷(As)、铍(Be)、硼(B)、镉(Cd)、钴(Co)、铜(Cu)、铁(Fe)、锰(Mn)、钼(Mo)、镍(Ni)、铅(Pb)、锂(Li)、铷(Rb)、硒(Se)、锶(Sr)和锌(Zn)的参考范围。将这些值与苏黎世动物园一小群患有糖尿病和双侧白内障的圈养平原棉尾兔的值进行了比较。此外,还描述了一种用于微量元素测定的全血样品消化方法。讨论了两组动物中微量元素浓度的显著差异。与白内障形成相比,未发现硒水平与其他微量元素水平之间存在相关性。

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