Vuorio E, Takala I, Pulkki K, Einola S
Scand J Rheumatol. 1979;8(3):173-6. doi: 10.3109/03009747909114451.
In studies with normal and rheumatoid synovial fibroblast cultures the effects of sodium aurothiomalate on the quantity and quality of hyaluronic acid were tested. This gold compound produced one clear effect: the molecular weight of hyaluronate produced by rheumatoid fibroblasts was increased (shifted towards normal) whereas the effects on the amounts of hyaluronic acid synthesized were small in both rheumatoid and control cultures. The importance of this finding in relation to the known beneficial effects of gold preparations in clinical medicine is discussed.
在对正常和类风湿性滑膜成纤维细胞培养物的研究中，测试了硫代苹果酸金钠对透明质酸数量和质量的影响。这种金化合物产生了一个明显的效果：类风湿性成纤维细胞产生的透明质酸盐的分子量增加（向正常水平转变），而在类风湿性和对照培养物中，对合成的透明质酸量的影响都很小。讨论了这一发现与金制剂在临床医学中已知的有益作用的关系。
