Froehlich H, Verma R
Department of Pediatrics, Kaiser Permanente Medical Center, Fresno, CA, USA.
Clin Infect Dis. 2001 Sep 15;33(6):906-8. doi: 10.1086/322585. Epub 2001 Aug 21.
A severe, local, inflammatory, late-phase reaction accompanied by skin necrosis occurred after an infant was given an intramuscular injection of recombinant hepatitis B virus vaccine. The clinical course and appearance of the rash were typical of an Arthus reaction. Although not identical to this case, prior reported cases of complement-mediated reactions occurring after hepatitis B virus infection or vaccination provide theoretical support for this diagnosis.
一名婴儿接受重组乙型肝炎病毒疫苗肌内注射后，出现了严重的局部炎症性迟发反应，并伴有皮肤坏死。皮疹的临床过程和表现符合阿瑟斯反应的典型特征。虽然与该病例不完全相同，但先前报道的乙型肝炎病毒感染或疫苗接种后发生补体介导反应的病例为这一诊断提供了理论支持。
