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[精神科门诊部141例成人注意力缺陷多动障碍(ADHD)患者的功能、共病情况及治疗]

[Functioning, comorbidity and treatment of 141 adults with attention deficit hyperactivity disorder (ADHD) at a psychiatric outpatient department].

作者信息

Kooij J J, Aeckerlin L P, Buitelaar J K

机构信息

GGZ Delfland, polikliniek Psychiatrie, Reinier de Graafweg 3-11, 2625 AD Delft.

出版信息

Ned Tijdschr Geneeskd. 2001 Aug 4;145(31):1498-501.

Abstract

OBJECTIVE

To describe the functioning, comorbidity and treatment of adults with attention deficit hyperactivity disorder (ADHD).

DESIGN

Retrospective.

METHOD

In the period 1 May 1995 to 31 January 1998, 141 patients aged 18-54 were diagnosed with ADHD at the Delfland Psychiatric Outpatients' Department, Delft, the Netherlands. For all of these patients, data concerning the functioning, comorbidity, and the response to treatment with clonidine (n = 34) or methylphenidate (n = 99), were collected from anamneses, hetero-anamneses and school reports.

RESULTS

The most frequent complaints were: mood-swings, rage-outbursts, sensation-seeking behaviour, sleeping disorders, anxiety and depressive symptoms. In 94% (n = 123) of the cases, childhood onset of ADHD symptoms was confirmed by a family member. The distribution of ADHD subtypes was comparable to the distribution in children. Psychiatric comorbidity was common. Treatment with methylphenidate was more effective and better tolerated than treatment with clonidine.

CONCLUSION

With respect to ADHD subtypes, patterns of comorbidity and effectiveness of medication, ADHD in the adults studied was comparable with what is known about ADHD in children.

摘要

目的

描述成人注意力缺陷多动障碍(ADHD)的功能表现、共病情况及治疗。

设计

回顾性研究。

方法

在1995年5月1日至1998年1月31日期间,荷兰代尔夫特市代尔夫兰精神科门诊部对141名年龄在18 - 54岁的患者进行了ADHD诊断。对于所有这些患者,从病历、他人提供的病历信息和学校报告中收集了有关其功能表现、共病情况以及使用可乐定(n = 34)或哌甲酯(n = 99)治疗反应的数据。

结果

最常见的主诉为:情绪波动、愤怒爆发、寻求刺激行为、睡眠障碍、焦虑和抑郁症状。94%(n = 123)的病例中,家庭成员证实ADHD症状始于童年。ADHD亚型的分布与儿童中的分布情况相当。精神科共病很常见。哌甲酯治疗比可乐定治疗更有效且耐受性更好。

结论

在所研究的成人中,就ADHD亚型、共病模式及药物疗效而言,ADHD与儿童ADHD的已知情况相当。

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