通过X射线吸收光谱法监测卡铂和奥沙利铂在氯化物介质中的分解。
Carboplatin and oxaliplatin decomposition in chloride medium, monitored by XAS.
作者信息
Curis E, Provost K, Bouvet D, Nicolis I, Crauste-Manciet S, Brossard D, Bénazeth S
机构信息
Laboratoire de Biomathématique - Faculté de Pharmacie, Université Paris 5, France.
出版信息
J Synchrotron Radiat. 2001 Mar 1;8(Pt 2):716-8. doi: 10.1107/s0909049500017775.
PMID:11512906
Abstract
The stability of carboplatin and oxaliplatin aqueous solutions has been studied under different chloride ions concentration and pH conditions. For both compounds, we demonstrate the chloration of the platinum first coordination shell.
摘要
已在不同氯离子浓度和pH条件下研究了卡铂和奥沙利铂水溶液的稳定性。对于这两种化合物，我们证明了铂第一配位层的氯化作用。
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