Takenaka F, Uchiyama H
Tatsuuma-honke Brewing Co. Ltd., Nishinomiya, Hyogo, Japan.
Biosci Biotechnol Biochem. 2001 Jul;65(7):1458-63. doi: 10.1271/bbb.65.1458.
Alpha-D-glucosylglycerol (GG) is a mixture of 2-O-alpha-D-glucosylglycerol (GG-II), (2R)-1-O-alpha-D-glucosylglycerol (R-GG-I) and (2S)-1-O-alpha-D-glucosylglycerol (S-GG-I). GG has been found to be slightly hydrolyzed in vitro only by rat intestinal enzymes, but hardly at all by other digestive juices. GG suppressed the hydrolysis of maltose, sucrose and isomaltose by rat intestinal enzymes because the amount of glucose in the digestion of a mixture of GG and disaccharide was less than the sum of that in each individual digestion. The consumption of GG was suppressed by isomaltose, but promoted by maltose, with the hydrolysis of GG being suppressed. Sucrose appeared to suppress only the consumption of S-GG-I, suggesting that S-GG-I was hydrolyzed by the active site of sucrase in a sucrase-isomaltase complex. Transglucosylation seems to have occurred more frequently in the individual digestion of maltose and isomaltose than in that of GG and sucrose. GG seemed to promote transglucosylation in the presence of maltose, to suppress it with sucrose, and to delay it with isomaltose.
α-D-葡糖基甘油（GG）是2-O-α-D-葡糖基甘油（GG-II）、（2R）-1-O-α-D-葡糖基甘油（R-GG-I）和（2S）-1-O-α-D-葡糖基甘油（S-GG-I）的混合物。已发现GG仅在体外被大鼠肠道酶轻微水解，但几乎不被其他消化液水解。GG抑制大鼠肠道酶对麦芽糖、蔗糖和异麦芽糖的水解，因为在GG和二糖混合物消化过程中葡萄糖的量少于每种单独消化中葡萄糖量的总和。异麦芽糖抑制GG的消耗，但麦芽糖促进GG的消耗，同时GG的水解受到抑制。蔗糖似乎仅抑制S-GG-I的消耗，这表明S-GG-I被蔗糖酶-异麦芽糖酶复合物中蔗糖酶的活性位点水解。转糖基化在麦芽糖和异麦芽糖的单独消化中似乎比在GG和蔗糖的单独消化中更频繁发生。GG在麦芽糖存在下似乎促进转糖基化，在蔗糖存在下抑制转糖基化，在异麦芽糖存在下延迟转糖基化。
