Bener A, Obineche E, Gillett M, Pasha M A, Bishawi B
Department of Community Medicine, Faculty of Medicine & Health Sciences, United Arab Emirates University, Al-Ain.
Int Arch Occup Environ Health. 2001 Jul;74(5):375-8. doi: 10.1007/s004200100231.
Previous studies have supported the association between high levels of blood lead levels (BLL) and elevated blood pressure. In addition, significant correlations between BLL and a variety of risk factors for blood pressure and diabetes mellitus have been well-established.
To examine the relationship between BLL, blood pressure and diabetes as well as other selected social and biochemical factors, among workers in the United Arab Emirates (UAE).
This comparative study included 110 industrial workers (exposed to lead in the workplace) and 110 non-industrial workers (not exposed); all were recruited in the city of Al-Ain, Abu-Dhabi Emirate, UAE and the groups were evenly matched for age, gender and nationality.
The industrial workers had a significantly higher mean of BLL (median 81 and geometric mean (GM) 62 microg/dl) than did non-industrial workers (median 11 and GM 13 microg/dl). In the present study, the lead-exposed group also had significantly higher blood lead levels, body-mass index (BMI), systolic and diastolic blood pressures, fasting blood glucose and plasma levels of total cholesterol, lactate dehydrogenase and uric acid than did the non-exposed group. Furthermore a significant correlation between BLL and systolic blood pressure was observed.
The study supports the hypothesis of a positive association between lead exposure, high blood pressure and risk of diabetes and heart disease.
先前的研究支持高血铅水平（BLL）与血压升高之间的关联。此外，BLL与多种血压和糖尿病风险因素之间的显著相关性已得到充分证实。
研究阿拉伯联合酋长国（阿联酋）工人中血铅水平（BLL）、血压和糖尿病以及其他选定的社会和生化因素之间的关系。
这项比较研究包括110名产业工人（工作场所接触铅）和110名非产业工人（未接触）；所有人员均在阿联酋阿布扎比酋长国艾因市招募，两组在年龄、性别和国籍方面均衡匹配。
产业工人的血铅水平均值显著高于非产业工人（中位数81，几何均值（GM）62微克/分升）（非产业工人中位数11，GM 13微克/分升）。在本研究中，铅暴露组的血铅水平、体重指数（BMI）、收缩压和舒张压、空腹血糖以及总胆固醇、乳酸脱氢酶和尿酸的血浆水平也显著高于未暴露组。此外，观察到血铅水平与收缩压之间存在显著相关性。
该研究支持铅暴露、高血压与糖尿病和心脏病风险之间呈正相关的假设。
