Nail S L, White J L, Hem S L
J Pharm Sci. 1975 Jul;64(7):1166-9. doi: 10.1002/jps.2600640707.
Data are presented which demonstrate the IR spectrophotometry is more sensitive than X-ray diffraction to structural changes occurring in aluminum hydroxide gel during aging. By examining changes in peak shape and position in the IR spectrum, evidence is seen for an increasing degree of order as the gel ages. The increased order may be responsible for the loss of acid reactivity observed during aging. IR analysis is also recommended for routine monitoring of aluminum hydroxide gels.
所呈现的数据表明，红外分光光度法比X射线衍射法对氢氧化铝凝胶老化过程中发生的结构变化更敏感。通过检查红外光谱中峰形和位置的变化，可以看出随着凝胶老化，有序度增加。这种增加的有序度可能是老化过程中观察到的酸反应性丧失的原因。还建议使用红外分析对氢氧化铝凝胶进行常规监测。
