Bennett M R, Florin T, Hall R
J Physiol. 1975 May;247(2):429-46. doi: 10.1113/jphysiol.1975.sp010939.
A study has been made of the effects of changing [Ca]O and [Mg]O on the binomial statistic parameters p and n which control the average quantal content (m) of the synaptic potential due to acetylcholine release. 2. When [Ca]O was varied in the range 0-1 to 1-0 mM, p increased as the first power of [Ca]O whereas n increased as the third power of [Ca]O. 3. Increasing [Mg]O depressed both p and n, however variations of [Ca]O in the presence of high [Mg]O did not significantly change the power relationship between either p and [Ca]O or between n and [Ca]O. 4. The facilitated increase in m during a short train was due to an increase in n, whereas the post-tetanic increase in m during a tetanus was due to an increase in p. These results are considered in terms of the role of Ca ions in facilitation and post-tetanic potentiation.
研究了改变[Ca]O和[Mg]O对二项式统计参数p和n的影响，这两个参数控制着因乙酰胆碱释放而产生的突触电位的平均量子含量（m）。2. 当[Ca]O在0.1至1.0 mM范围内变化时，p随[Ca]O的一次幂增加，而n随[Ca]O的三次幂增加。3. 增加[Mg]O会使p和n都降低，然而在高[Mg]O存在的情况下改变[Ca]O，p与[Ca]O或n与[Ca]O之间的幂关系没有显著变化。4. 在短串刺激期间m的易化增加是由于n的增加，而在强直刺激期间强直后m的增加是由于p的增加。根据钙离子在易化和强直后增强中的作用对这些结果进行了讨论。
