Lachance L, Sowers M, Jamadar D, Jannausch M, Hochberg M, Crutchfield M
School of Public Health, University of Michigan, Ann Arbor, 48109, USA.
Osteoarthritis Cartilage. 2001 Aug;9(6):527-32. doi: 10.1053/joca.2000.0429.
Discrepancies exist between radiographic osteoarthritis of the knee (OAK) and report of knee joint pain. Little is known about how these two definitions of osteoarthritis (OA) and their correlates differ between African American (AA) and Caucasian (CA) women.
We compared the prevalence of radiographic OAK and knee joint pain in AA and CA women, and the congruency of these outcomes according to age, body size, and knee injury.
A cross-sectional study of African American and Caucasian women aged 40-53 years (N=829) in Southeast Michigan used the Kellgren and Lawrence Atlas of Standard Radiographs of Arthritis to characterize radiographs of both knee joints (weight bearing) and self-report of knee pain.
Current pain was a significantly more sensitive predictor of radiographic OAK among AA women (Se=0.51) compared to CA women (Se=0.35). Specificity was similar between AA women (Sp=0.77) and CA women (Sp=0.82). Positive predictive value was significantly greater for AA compared with CA women (PV+=0.40 and PV+=0.15, respectively). The odds of having radiographic OAK increased with BMI >32 kg/m(2) in both groups. Knee pain was related to BMI in CA women, but not AA women. Previous knee injury was associated with knee pain in both AA and CA women (OR=3.0 and OR=2.4).
Joint pain in AA women was more likely to be associated with radiographic OAK as compared with CA women. This suggests differences in these two groups in both how pain is experienced in the OAK process and in the prevalence of non-OAK related pain in knee joints.
膝关节的影像学骨关节炎（OAK）与膝关节疼痛报告之间存在差异。对于非裔美国（AA）女性和白人（CA）女性而言，这两种骨关节炎（OA）定义及其相关因素有何不同，目前知之甚少。
我们比较了AA和CA女性中影像学OAK和膝关节疼痛的患病率，以及根据年龄、体型和膝关节损伤情况这些结果的一致性。
对密歇根州东南部年龄在40 - 53岁的非裔美国和白人女性（N = 829）进行的一项横断面研究，使用《凯尔格伦和劳伦斯关节炎标准X线图谱》对双膝关节（负重位）X线片进行特征描述，并采用膝关节疼痛的自我报告。
与CA女性（敏感性=0.35）相比，当前疼痛在AA女性中是影像学OAK更敏感的预测指标（敏感性=0.51）。AA女性（特异性=0.77）和CA女性（特异性=0.82）之间的特异性相似。与CA女性相比，AA女性的阳性预测值显著更高（分别为阳性预测值=0.40和阳性预测值=0.15）。两组中体重指数（BMI）>32 kg/m²时，出现影像学OAK的几率均增加。膝关节疼痛与CA女性的BMI相关，但与AA女性无关。既往膝关节损伤在AA和CA女性中均与膝关节疼痛相关（比值比分别为3.0和2.4）。
与CA女性相比，AA女性的关节疼痛更有可能与影像学OAK相关。这表明这两组在OAK过程中疼痛的体验方式以及膝关节非OAK相关疼痛的患病率方面存在差异。
