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从网球花的鳞茎中分离出的五种新的多氧胆甾烷双糖链皂苷。

Five new polyoxygenated cholestane bisdesmosides from the bulbs of Galtonia candicans.

作者信息

Mimaki Y, Kuroda M, Yokosuka A, Sashida Y

机构信息

Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432-1, Horinouchi, Hachioji, Tokyo 192-0392, Japan.

出版信息

J Nat Prod. 2001 Aug;64(8):1069-72. doi: 10.1021/np010208d.

DOI:10.1021/np010208d
PMID:11520229
Abstract

Two new cholestane bisdesmosides (1, 2) based upon (22S)-cholest-5-ene-3 beta,16 beta,22-triol with an acetyl group at the sugar moiety and three new ones (3-5) based upon (22S)-cholest-5-ene-1 beta,3 beta,16 beta,22-tetrol, along with a known cholestane glycoside, were isolated from the bulbs of Galtonia candicans. The structures of the new compounds were determined by spectroscopic analysis and chemical transformations.

摘要

从网球花的鳞茎中分离出两种基于(22S)-胆甾-5-烯-3β,16β,22-三醇且糖部分带有乙酰基的新胆甾烷双糖苷(1, 2),以及三种基于(22S)-胆甾-5-烯-1β,3β,16β,22-四醇的新化合物(3 - 5),还有一种已知的胆甾烷糖苷。通过光谱分析和化学转化确定了新化合物的结构。

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引用本文的文献

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Galtonosides A-E: Antiproliferative and Antiplasmodial Cholestane Glycosides from .高桐醇 A-E:来自. 的具有抗增殖和抗疟原虫活性的甾体糖苷
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Structural Characterization of Cholestane Rhamnosides from Ornithogalum saundersiae Bulbs and Their Cytotoxic Activity against Cultured Tumor Cells.虎眼万年青鳞茎中胆甾烷鼠李糖苷的结构表征及其对培养肿瘤细胞的细胞毒性活性
Molecules. 2017 Jul 25;22(8):1243. doi: 10.3390/molecules22081243.