Kuroda M, Mimaki Y, Yokosuka A, Sashida Y
Laboratory of Medicinal Plant Science, School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan.
Chem Pharm Bull (Tokyo). 2001 Aug;49(8):1042-6. doi: 10.1248/cpb.49.1042.
Further search for cytotoxic compounds contained in the bulbs of Galtonia candicans (Liliaceae) led to the isolation of four potent cytotoxic cholestane glycosides (1-4) based upon 3beta,16beta,17alpha-trihydroxycholest-5-en-22-one, three of which (2-4) have not been reported previously. A new cholestane bisdesmoside (5) and a new rearranged cholestane glycoside (6) were also isolated. The structural assignment of the new constituents was carried out by spectroscopic analysis and a few chemical transformations.
对网球花（石蒜科）鳞茎中所含细胞毒性化合物的进一步研究，导致基于3β,16β,17α-三羟基胆甾-5-烯-22-酮分离出四种强效细胞毒性胆甾烷糖苷（1-4），其中三种（2-4）此前未见报道。还分离出一种新的胆甾烷双糖链苷（5）和一种新的重排胆甾烷糖苷（6）。通过光谱分析和一些化学转化对新成分进行了结构鉴定。
