Helmer R E, Sayle B A, Alperin J B, Gardner F H
Acta Haematol. 1979;61(6):330-3. doi: 10.1159/000207682.
A patient with sickle cell anemia was hospitalized because of an acute erythropoietic aplastic crisis. 111In chloride bone marrow scintigraphy performed during the aplastic crisis showed markedly impaired uptake of the radionuclide and simultaneous 59Fe clearance T 1/2 studies were prolonged (420.9 min). Following recovery from the aplastic crisis 111In scintigraphy revealed an expanded marrow and the radioiron clearance T 1/2 was accelerated (20.9 min). The clinical course, hemograms and bone marrow aspirations correlated with marrow scintigraphy. 111In appears to be a valuable marrow scanning agent for assessing the presence of intramedullary erythropoietic activity.
一名镰状细胞贫血患者因急性红细胞生成障碍性危象入院。再生障碍性危象期间进行的氯化铟-111骨髓闪烁扫描显示放射性核素摄取明显受损，同时59铁清除半衰期研究延长（420.9分钟）。再生障碍性危象恢复后，铟-111闪烁扫描显示骨髓扩张，放射性铁清除半衰期加快（20.9分钟）。临床病程、血常规和骨髓穿刺结果与骨髓闪烁扫描结果相关。铟-111似乎是一种评估骨髓内红细胞生成活性的有价值的骨髓扫描剂。
