McCallum S J, Corkill J, Gallagher M, Ledson M J, Hart C A, Walshaw M J
Lancet. 2001 Aug 18;358(9281):558-60. doi: 10.1016/s0140-6736(01)05715-4.
Infection with transmissible strains of Pseudomonas aeruginosa can occur in uncolonised patients, but cross infection (superinfection) of patients already colonised withP aeruginosa has not been reported. With genotypic identification, we found superinfection by a multiresistant transmissible strain of P aeruginosa in four patients with cystic fibrosis (CF) who were already colonised by unique strains of P aeruginosa. No evidence of environmental contamination was found, but all patients became superinfected after contact with colonised individuals during inpatient stays. Inpatients with CF who are colonised with P aeruginosa should be separated by strain type. Such strain typing can only be reliably done by genomic methods, but this has resource implications.
铜绿假单胞菌的可传播菌株感染可发生在未被定植的患者中，但尚未有关于已被铜绿假单胞菌定植的患者发生交叉感染（重复感染）的报道。通过基因分型，我们在4例已被铜绿假单胞菌独特菌株定植的囊性纤维化（CF）患者中发现了由多重耐药可传播铜绿假单胞菌菌株引起的重复感染。未发现环境污染的证据，但所有患者在住院期间与定植个体接触后均发生了重复感染。已被铜绿假单胞菌定植的CF住院患者应按菌株类型进行隔离。这种菌株分型只能通过基因组方法可靠地完成，但这会涉及资源问题。
