Ovchinnikov L P, Skabkin M A, Ruzanov P V, Evdokimova V M
Mol Biol (Mosk). 2001 Jul-Aug;35(4):548-58.
The properties of two universal major proteins of cytoplasmic mRNP, p50 and the poly(A)-binding protein (PABP), are summarized. Their roles in formation of polyribosomal and free inactive mRNP are considered, with the focus on the authors' studies of p50. The parts these mRNP proteins play in translation regulation, stability, and localization of mRNA are described, and the the possible mechanisms of their function are discussed.
总结了细胞质mRNP的两种普遍主要蛋白质——p50和聚腺苷酸结合蛋白（PABP）的特性。考虑了它们在多核糖体和游离无活性mRNP形成中的作用，重点是作者对p50的研究。描述了这些mRNP蛋白质在mRNA翻译调控、稳定性和定位中所起的作用，并讨论了它们可能的功能机制。
