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[远端泌尿生殖-肛门生殖道人乳头瘤病毒感染中的阴道镜检查]

[Colposcopy in human papilloma virus infections of the distal uro-ano-genital tract].

作者信息

Peroni M, Visci P

机构信息

Unità Operativa Malattie a Trasmissione Sessuale della Sfera Genitale Femminile, Istituto di Ricovero e Cura a Carattere-Scientifico "L. Spallanzani", Roma.

出版信息

Minerva Ginecol. 2000 Dec;52(12 Suppl 1):59-67.

Abstract

HPV infections fall within the STDs and certain high-risk types have a significant role in the cancer genesis of the distal genital tract. The infection results can be clinically evident or be subclinical and in this latter case they are revealed by a highly-sensitive colposcopic examination after acetic acid application at 3% followed by Schiller's test with Lugol solution in weak iodine concentration. Indeed, the distal districts of male and female uroano-genital tracts takes advantage of the colposcopic diagnostics although complementary analysis like histology or DNA tests for HPV typing have sometimes to be performed to confirm the results or to evaluate the prognosis. HPV subclinical lesions, above all at cervical and vaginal level, are those mostly involved with the cancer genesis: the bright-white acidophilia often combined with irregular surface, atypical vascularization and discrete iodine caption represents a colposcopic indication to complementary diagnostic analysis aiming at choosing the most suitable therapy for which colposcopy can show the lesion topography and its frequent plurilocalizations.

摘要

人乳头瘤病毒(HPV)感染属于性传播疾病,某些高危型HPV在远端生殖道癌症发生中起重要作用。感染结果在临床上可能明显,也可能是亚临床的,在后一种情况下,在涂抹3%醋酸后进行高灵敏度阴道镜检查,随后用低浓度碘的卢戈氏溶液进行席勒试验可发现这些感染。实际上,男性和女性泌尿生殖道的远端区域可借助阴道镜诊断,尽管有时需要进行组织学或HPV分型DNA检测等补充分析来确认结果或评估预后。HPV亚临床病变,尤其是宫颈和阴道部位的病变,大多与癌症发生有关:亮白色嗜酸反应常伴有表面不规则、非典型血管形成和碘摄取异常,这是阴道镜提示进行补充诊断分析的表现,目的是选择最合适的治疗方法,阴道镜可为其显示病变的形态及其常见的多部位分布情况。

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