Danel V C, Wiart J F, Hardy G A, Vincent F H, Houdret N M
Département Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire, Grenoble, France.
J Toxicol Clin Toxicol. 2001;39(4):409-11. doi: 10.1081/clt-100105163.
A 44-year-old man ingested about 40 flowers of Colchicum autumnale L. The patient presented with nausea, vomiting, and abdominal pain 2 hours after ingestion and had diarrhea 14 hours after ingestion. Hematological values remained within normal range. Treatment was mainly supportive. The outcome was favorable. The intoxication was confirmed by high-performance liquid chromatography-mass spectrometry. Maximal colchicine levels were 4.34 ng/mL at 13 hours in plasma and 5.43 ng/mL at 16 hours in erythrocytes.
We report one of the few symptomatic cases of Colchicum autumnale L. poisoning confirmed by toxicological analysis.
一名44岁男子摄入了约40朵秋水仙。患者在摄入后2小时出现恶心、呕吐和腹痛，摄入后14小时出现腹泻。血液学指标保持在正常范围内。治疗主要是支持性的。结果良好。通过高效液相色谱-质谱法确认了中毒情况。血浆中秋水仙碱最高水平在13小时时为4.34纳克/毫升，红细胞中在16小时时为5.43纳克/毫升。
我们报告了少数经毒理学分析确诊的秋水仙中毒有症状病例之一。
