Effect of phlebography on 125I uptake test.

Increased 125I fibrinogen uptake counts were encountered in 30 of 55 limbs after a normal ascending phelbogram. In most cases, the abnormal 125I fibrinogen uptake test occurred within 72 hr after phlebography, and the elevated counts were most frequently seen around the ankle, with contiguous involvement of the calf seen less often. Inly three patients with positive counts subsequently became symptomatic and were treated for deep venous thrombosis. The presence of deep venous thrombosis was confirmed by repeat ascending phlebography in two of these cases. Ascending phlebography was not performed on the other positive postphlebographic fibrinogen uptake test limbs.