García-Garmendia J L, Ortiz-Leyba C, Garnacho-Montero J, Jiménez-Jiménez F J, Pérez-Paredes C, Barrero-Almodóvar A E, Gili-Miner M
Intensive Care Unit, University Hospital Virgen del Rocío, Seville, Spain.
Clin Infect Dis. 2001 Oct 1;33(7):939-46. doi: 10.1086/322584. Epub 2001 Aug 22.
Nosocomial bacteremia caused by Acinetobacter baumannii (AB) is of increasing concern in critically ill patients, and the risk factors for this infection are not well established. An inception cohort study in a 40-bed medical and surgical intensive care unit (ICU) at a single institution was conducted during a 2-year period to determine the risk factors for AB nosocomial bacteremia. Risk factors related to the underlying diseases, the clinical picture at admission, and those acquired during the stay in the ICU were recorded upon admission and daily throughout the ICU stay. We defined an "invasive procedures index" as the number of invasive procedures performed every day during the ICU stay before the onset of AB bacteremia divided by the number of days in the ICU before the onset of AB bacteremia. Risk factors that were independently associated with AB bacteremia were immunosuppression, unscheduled admission to the hospital, respiratory failure at ICU admission, previous antimicrobial therapy, previous sepsis in the ICU, and the invasive procedures index.
鲍曼不动杆菌（AB）引起的医院感染性菌血症在重症患者中日益受到关注，且这种感染的危险因素尚未完全明确。在一家机构的40张床位的内科和外科重症监护病房（ICU）进行了一项为期2年的队列研究，以确定AB医院感染性菌血症的危险因素。入院时及在ICU住院期间每日记录与基础疾病、入院时临床表现以及在ICU住院期间获得的危险因素。我们将“侵入性操作指数”定义为AB菌血症发作前在ICU住院期间每天进行的侵入性操作数量除以AB菌血症发作前在ICU的住院天数。与AB菌血症独立相关的危险因素包括免疫抑制、非计划入院、ICU入院时呼吸衰竭、先前的抗菌治疗、先前在ICU发生的败血症以及侵入性操作指数。
