Henderson D A, Fenner F
The Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21202, USA.
Clin Infect Dis. 2001 Oct 1;33(7):1057-9. doi: 10.1086/323808. Epub 2001 Aug 22.
To destroy all remaining stocks of variola virus on or before 31 December 2002 seems an even more compelling goal today than it did in 1999, when the 52d World Health Assembly authorized temporary retention of remaining stocks to facilitate the possible development of (1) a more attenuated, less reactogenic smallpox vaccine and (2) an antiviral drug that could be used in treatment of patients with smallpox. We believe the deadline established in 1999 should be adhered to, given the potential outcomes of present research. Although verification that every country will have destroyed its stock of virus is impossible, it is reasonable to assume that the risk of a smallpox virus release would be diminished were the World Health Assembly to call on each country to destroy its stocks of smallpox virus and to state that any person, laboratory, or country found to have virus after date x would be guilty of a crime against humanity.
在2002年12月31日或之前销毁所有剩余的天花病毒储备，如今看来是一个比1999年更具紧迫性的目标。1999年，第52届世界卫生大会批准暂时保留剩余储备，以促进可能研发出（1）一种毒性更低、反应原性更小的天花疫苗，以及（2）一种可用于治疗天花患者的抗病毒药物。鉴于当前研究的潜在结果，我们认为应该遵守1999年设定的最后期限。虽然无法核实每个国家是否都会销毁其病毒储备，但可以合理地假设，如果世界卫生大会呼吁各国销毁其天花病毒储备，并声明在x日期之后发现仍有病毒的任何个人、实验室或国家将犯下危害人类罪，天花病毒释放的风险将会降低。
