对青少年类风湿性关节炎患者体内发现的组织相容性抗原的重新检测。
Re-examination of histocompatibility antigens found in patients with juvenile rheumatoid arthritis.
作者信息
Gibson D J, Carpenter C M, Stillman J S, Schur P H
出版信息
N Engl J Med. 1975 Sep 25;293(13):636-8. doi: 10.1056/NEJM197509252931305.
One hundred and twenty-three patients with juvenile rheumatoid arthritis and a similar number of controls were tissue typed for 30 HL-A antigens to determine if there were any associations between particular HL-A antigens and the disease. None were found. However, HL-A7 was found more frequently in patients with juvenile rheumatoid arthritis demonstrating tenosynovitis than in the population with juvenile rheumatoid arthritis as a whole. These observations fail to support the contention of others that HL-A-W27 is found more frequently than expected in such patients.
对123例青少年类风湿性关节炎患者和数量相近的对照组进行了30种HL-A抗原的组织分型，以确定特定的HL-A抗原与该疾病之间是否存在关联。未发现有任何关联。然而，在患有腱鞘炎的青少年类风湿性关节炎患者中，HL-A7的出现频率高于整个青少年类风湿性关节炎患者群体。这些观察结果并不支持其他人的观点，即在这类患者中HL-A-W27的出现频率高于预期。
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