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卡塔格内综合征与类风湿关节炎:一种不寻常的关联。

Kartagener's syndrome and rheumatoid arthritis: an unusual association.

作者信息

Riente L, Fadda P, Mazzantini M, Frigelli S, Fattori B, Neri E

机构信息

University of Pisa, Italy.

出版信息

Clin Rheumatol. 2001;20(4):282-4. doi: 10.1007/s100670170047.

Abstract

We report the case of a 66-year-old caucasian woman affected by Kartagener's syndrome (KS), a genetically transmitted disorder characterised by situs viscerum inversus, bronchiectasis and sinusitis, who also developed rheumatoid arthritis (RA). The impaired mucociliary function typical of KS caused recurrent paranasal sinus and lung infections, as shown by CT scans of the sinuses and chest. The coexistence of KS and RA in our patient was probably accidental. Given the small number of patients in whom an association of the two disorders has been described, it is impossible to establish whether KS might play a role in the pathogenesis of RA.

摘要

我们报告了一例66岁的白种女性,她患有卡塔格纳综合征(KS),这是一种常染色体隐性遗传疾病,特征为内脏转位、支气管扩张和鼻窦炎,该患者还患有类风湿关节炎(RA)。KS典型的黏液纤毛功能受损导致鼻窦和肺部反复感染,鼻窦和胸部的CT扫描结果证实了这一点。我们这位患者中KS与RA的并存可能是偶然的。鉴于已描述的同时患有这两种疾病的患者数量较少,因此无法确定KS是否可能在RA的发病机制中发挥作用。

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