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侵入性心血管手术使用方面的种族差异:文献综述及未来研究建议

Racial differences in the use of invasive cardiovascular procedures: review of the literature and prescription for future research.

作者信息

Kressin N R, Petersen L A

机构信息

Center for Health Quality, Outcomes and Economic Research, Veterans Affairs Medical Center, 200 Springs Road, Building 70 (152), Bedford, MA 01730, USA.

出版信息

Ann Intern Med. 2001 Sep 4;135(5):352-66. doi: 10.7326/0003-4819-135-5-200109040-00012.

Abstract

PURPOSE

The cause of racial disparities in the use of invasive cardiac procedures remains unclear. To summarize, evaluate, and clarify gaps in the literature, studies examining racial differences in cardiac catheterization, percutaneous transluminal coronary angioplasty (PTCA), and coronary artery bypass grafting (CABG) were reviewed.

DATA SOURCES

MEDLINE search for English-language articles published from 1966 to May 2000.

STUDY SELECTION

Empirical studies of adults.

DATA EXTRACTION

The odds ratios for procedure use by race were examined for each study; cohorts and covariates were also documented.

DATA SYNTHESIS

Literature was classified as one of three groups on the basis of study design. For the first group, which used administrative data, odds ratios (ORs) for African-American patients compared with white patients ranged from 0.41 to 0.94 for cardiac catheterization, from 0.32 to 0.80 for PTCA, and from 0.23 to 0.68 for CABG. Procedure rates were also lower for Hispanic and Asian patients. In the second group, which used detailed clinical data, African-American patients remained disproportionately less likely to receive cardiac catheterization (OR, 0.03 to 0.85), PTCA (OR, 0.20 to 0.87), and CABG (OR, 0.22 to 0.68). A few studies noted that Hispanic and Asian patients were also disproportionately less likely to receive such procedures. The third group used survey methods but found conflicting results regarding patient refusals as a source of racial variation. Less-educated patients and patients who were not as experienced with the procedure were more likely to decline PTCA. Physician bias was also associated with racial variation in recommendations for treatment.

CONCLUSIONS

Racial differences in invasive cardiac procedure use were found even after adjustment for disease severity. Future studies should comprehensively and simultaneously examine the full range of patient, physician, and health care system variables related to racial differences in the provision of invasive cardiac procedures.

摘要

目的

侵入性心脏手术使用方面种族差异的原因尚不清楚。为了总结、评估并澄清文献中的差距,我们对研究心脏导管插入术、经皮腔内冠状动脉成形术(PTCA)和冠状动脉旁路移植术(CABG)中种族差异的研究进行了综述。

数据来源

对1966年至2000年5月发表的英文文章进行MEDLINE检索。

研究选择

针对成年人的实证研究。

数据提取

检查每项研究中按种族划分的手术使用比值比;同时记录队列和协变量。

数据综合

根据研究设计,文献被分为三组之一。对于第一组,即使用行政数据的组,非裔美国患者与白人患者相比,心脏导管插入术的比值比(OR)为0.41至0.94,PTCA为0.32至0.80,CABG为0.23至0.68。西班牙裔和亚裔患者的手术率也较低。在第二组,即使用详细临床数据的组,非裔美国患者接受心脏导管插入术(OR,0.03至0.85)、PTCA(OR,0.20至0.87)和CABG(OR,0.22至0.68)的可能性仍然不成比例地较低。一些研究指出,西班牙裔和亚裔患者接受此类手术的可能性也不成比例地较低。第三组使用调查方法,但在将患者拒绝作为种族差异来源方面发现了相互矛盾的结果。受教育程度较低的患者以及对该手术经验不足的患者更有可能拒绝PTCA。医生偏见也与治疗建议中的种族差异有关。

结论

即使在调整疾病严重程度后,侵入性心脏手术使用方面的种族差异仍然存在。未来的研究应全面并同时检查与侵入性心脏手术提供方面的种族差异相关的患者、医生和医疗保健系统的所有变量。

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