Zetzsche T, Meisenzahl E M, Preuss U W, Holder J J, Kathmann N, Leinsinger G, Hahn K, Hegerl U, Möller H J
Department of Psychiatry, University of Munich, Ludwig-Maximilians University, Nussbaumstr. 7, 80336 Munich, Germany.
Psychiatry Res. 2001 Aug 25;107(2):99-115. doi: 10.1016/s0925-4927(01)00087-7.
The aim of our study was to examine whether the degree of planum temporale (PT) asymmetry and the possible correlation of morphological PT asymmetries with handedness are influenced by the definition of PT borders. For this reason, we applied three different anatomical PT definitions formerly used in the literature. The PT total (with the end of the Sylvian fissure (SF) as its posterior border) was separated into anterior and posterior regions. The border between anterior and posterior PT was set according to the following definitions: at the end of Heschl's gyrus (1st definition); at the start of the ascending SF ramus according to the 'knife-cut' method (2nd definition); and at the bifurcation of the SF (3rd definition). Thirty right-handed healthy men were recruited. MRI data sets analyzed with the software program BRAINS were used for in vivo PT volumetry. The Edinburgh Handedness Inventory (EHI) and the Hand Dominance Test were used to determine the degree of handedness. In summary, we detected that the type and the degree of asymmetry between left and right PT were strongly dependent on the definition used for PT borders: a left>right asymmetry was found in all PT regions, except a right>left asymmetry of the anterior PT according to our 1st PT definition (lateral to Heschl's gyrus) and a symmetry of the posterior PT according to our 3rd PT definition (posterior to SF bifurcation). In addition, a significant correlation was found between the degree of handedness measured by the EHI and the right posterior PT (3rd definition). We conclude that the influence of the definition of PT borders on the investigated variables may explain some of the variances between former investigations on PT asymmetry and handedness. The possible implications of the correlation between handedness and the extension of the right parietal PT are discussed and have to be elucidated by further studies.
我们研究的目的是检验颞平面（PT）不对称程度以及PT形态不对称与利手之间的可能相关性是否受PT边界定义的影响。因此，我们应用了文献中先前使用的三种不同的解剖学PT定义。将整个PT（以外侧裂（SF）末端为其后边界）分为前部和后部区域。前后PT之间的边界根据以下定义设定：在颞横回末端（第一种定义）；根据“刀切”法在上升的SF支起始处（第二种定义）；以及在SF分叉处（第三种定义）。招募了30名右利手健康男性。使用软件程序BRAINS分析的MRI数据集用于活体PT体积测量。使用爱丁堡利手量表（EHI）和利手优势测试来确定利手程度。总之，我们发现左右PT之间不对称的类型和程度强烈依赖于用于PT边界的定义：在所有PT区域均发现左>右不对称，但根据我们的第一种PT定义（颞横回外侧）前部PT为右>左不对称，根据我们的第三种定义（SF分叉后方）后部PT为对称。此外，发现EHI测量的利手程度与右侧后部PT（第三种定义）之间存在显著相关性。我们得出结论，PT边界定义对所研究变量的影响可能解释了先前关于PT不对称和利手性研究之间的一些差异。讨论了利手与右侧顶叶PT延伸之间相关性的可能含义，并且必须通过进一步研究加以阐明。
