Foundas A L, Leonard C M, Heilman K M
Department of Psychiatry and Neurology, Tulane University School of Medicine, New Orleans, La, USA.
Arch Neurol. 1995 May;52(5):501-8. doi: 10.1001/archneur.1995.00540290091023.
To explore the relationship between morphologic cerebral asymmetries of the pars triangularis (PTr) and the planum temporale (PT) measured on three-dimensional, gradient-echo, magnetic resonance imaging scans of healthy right- and left-handed subjects.
(Blinded) comparison of healthy right- and left-handed subjects who underwent magnetic resonance imaging.
The Seimens 1-T Magnetom (Seimens, Iselin, NH) at the University of Florida Health Science Center, Gainesville.
Healthy right-handed (n = 8) and left-handed (n = 8) subjects matched for age, sex, and educational level.
(1) Average length of the PTr (anterior ascending and anterior descending rami), (2) average length of the PT, (3) asymmetry quotients ([left-right]/[(left+right) (0.5)]) of the PTr and PT, and (4) combined asymmetry quotients of the PTr and PT.
There was a significant leftward asymmetry of the PTr and PT in the right-handed subjects, but there was no significant asymmetry in the left-handed subjects. When the combined asymmetry quotient of the PTr and PT was calculated, the right-handed subjects had a leftward asymmetry (87.5% [n = 7]) or left was equal to right (12.5% [n = 1]), and the left-handed subjects had a leftward asymmetry (62.5% [n = 5]), left was equal to right (12.5% [n = 1]), or a rightward asymmetry (25% [n = 2]). In the left-handed subjects, writing posture seemed to predict these combined asymmetry quotients, ie, left-handed subjects using an inverted writing posture had a leftward asymmetry and left-handed subjects using a non-inverted writing posture had a rightward asymmetry of the perisylvian speech-language regions.
On three-dimensional, gradient-echo, magnetic resonance imaging scans, we found a significant leftward asymmetry of the PTr and PT. When the groups were divided into right- and left-handed subjects, the former had a significant leftward asymmetry of the PTr and PT, while the latter did not. Measurements of the PTr and PT appear to be important indexes of the known functional asymmetries of the perisylvian speech-language regions.
通过对健康右利手和左利手受试者进行三维梯度回波磁共振成像扫描，探讨颞叶三角区（PTr）和颞平面（PT）的形态学脑不对称性之间的关系。
对接受磁共振成像的健康右利手和左利手受试者进行（盲法）比较。
佛罗里达大学健康科学中心盖恩斯维尔分校的西门子1-T Magnetom（西门子，伊瑟林，新罕布什尔州）。
年龄、性别和教育水平相匹配的健康右利手（n = 8）和左利手（n = 8）受试者。
（1）PTr（前升支和前降支）的平均长度，（2）PT的平均长度，（3）PTr和PT的不对称商（[左-右]/[（左+右）×0.5]），以及（4）PTr和PT的联合不对称商。
右利手受试者的PTr和PT存在显著的左侧不对称，但左利手受试者无显著不对称。计算PTr和PT的联合不对称商时，右利手受试者存在左侧不对称（87.5% [n = 7]）或左右相等（12.5% [n = 1]），左利手受试者存在左侧不对称（62.5% [n = 5]）、左右相等（12.5% [n = 1]）或右侧不对称（25% [n = 2]）。在左利手受试者中，书写姿势似乎可预测这些联合不对称商，即采用倒写姿势的左利手受试者存在左侧不对称，而采用非倒写姿势的左利手受试者在外侧裂周围语言区存在右侧不对称。
在三维梯度回波磁共振成像扫描中，我们发现PTr和PT存在显著的左侧不对称。当将研究对象分为右利手和左利手受试者时，前者的PTr和PT存在显著的左侧不对称，而后者则没有。PTr和PT的测量似乎是外侧裂周围语言区已知功能不对称的重要指标。
