Roberson R H, Trujillo T
Poult Sci. 1975 May;54(3):715-21. doi: 10.3382/ps.0540715.
The effect of two levels each of methionine (0.0 and 0.07 percent), thiouracil (0.0 and 0.05 percent), dienestrol diacetate (0.0 and 0.007 percent), and thyroactive casein (0.0 and 0.0125 percent) on the performancy, organ changes, and liver composition in 640 pullets of two strains was studied in a 24 factorial arrangement of treatments. Egg production, egg characteristics, feed conversion, organ weights, and liver composition were parameters measured. Supplemental methionine increased the phosphorus content of liver fat in strain A, but other parameters in the two strains were mot affected by the increase in dietary methionine. The thiouracil increased weight grains, gram of fat per total liver, percent of liver fat, thyroid weight, and heart weight but decreased the phosphorus content of liver fat. Nine typical cases of fatty liver syndrome with large liver hematomas occurred in the thiouracil treated birds and one case occurred in an untreated pullet. Dienestrol diacetate did not affect egg production, egg characteristics, organ weights, and liver composition in the two strains. Thyroprotein decreased weight gain, abdominal fat, liver weight. liver fat, thyroid weight, and percent red cells, but decreased percent blood sports in eggs and adjusted weights of the kidney and heart in both strains.
以2×2×2×2析因设计处理方式，研究了蛋氨酸（0.0%和0.07%）、硫脲嘧啶（0.0%和0.05%）、二乙酸己烯雌酚（0.0%和0.007%）以及甲状腺活性酪蛋白（0.0%和0.0125%）的两个水平对两个品系640只小母鸡生产性能、器官变化及肝脏成分的影响。测定的参数包括产蛋量、蛋的特性、饲料转化率、器官重量和肝脏成分。添加蛋氨酸增加了A品系肝脏脂肪中的磷含量，但两个品系的其他参数未受日粮蛋氨酸增加的影响。硫脲嘧啶增加了肝脏重量、每克肝脏的脂肪含量、肝脏脂肪百分比、甲状腺重量和心脏重量，但降低了肝脏脂肪中的磷含量。硫脲嘧啶处理组的鸡出现了9例伴有大的肝脏血肿的典型脂肪肝综合征病例，未处理的小母鸡中出现1例。二乙酸己烯雌酚对两个品系的产蛋量、蛋的特性、器官重量和肝脏成分均无影响。甲状腺蛋白降低了两个品系的体重增加、腹部脂肪、肝脏重量、肝脏脂肪、甲状腺重量和红细胞百分比，但降低了蛋中血斑的百分比以及肾脏和心脏的校正重量。
